Cal Thacker, a would-be artist, shares his slum living quarters with Mike Rubel, a pusher who exists in a private drug-centered world, and Richard Stoney Morgan, an embittered drifter who sponges from the other two. Cal's girl friend, Carrie, who has provided his only meaningful human contact, finds him in bed with another girl and breaks up with him. In despair, Cal tries unsuccessfully to obtain funds by selling his paintings. His motorcycle is wrecked in a crash, though Cal miraculously escapes injury. Later in the day, the three roommates meet at the apartment and attempt to obliterate their problems with cheap whiskey.
