Atelier Lydie & Suelle: The Alchemists and the Mysterious Paintings (2017)

The 19th main game in the Atelier franchise and third game in the Mysterious game trilogy. The game features two main characters and changes some of the previous game's systems. A new crafting feature, called Enchanting Agents, was added to the Synthesis system. 6 characters participate in combat, each attacker can have a support characters to help out, and you can now craft items while in combat.