Dedé Santana
- Born
- 29 April 1936 (90 years)
- Place of birth
- Niterói, Rio de Janeiro, Brazil
- Gender
- Male
Manfried Sant'Anna (Niterói, April 29, 1936), known artistically as Dedé Santana, is a Brazilian comedian, actor, director and screenwriter. Best known for his role in the television series Os Trapalhões, where he was one of the four protagonists.
