Luis Ospina
- Born
- 14 June 1949 (70 years old)
- Died
- 27 September 2019
- Place of birth
- Cali, Colombia
- Gender
- Male
Luis Ospina (14 June 1949 – 27 September 2019) was a Colombian film director. He is one of the founders of Caliwood film movement along with Carlos Mayolo and Andrés Caicedo.
